FTS
Also written as: FTS — First Trimester Screening
First trimester screening combining maternal age, ultrasound measurements, and biochemical markers to assess chromosomal abnormality risk.
Full Definition
First trimester screening (FTS) is a combined screening test performed between 10-14 weeks of pregnancy to assess the risk of chromosomal abnormalities, particularly Down syndrome and other trisomies. The screening incorporates maternal age as a risk factor, ultrasound measurements including nuchal translucency and crown-rump length, and maternal serum biochemical markers (free beta-hCG and PAPP-A). The results are combined using statistical algorithms to generate a personalized risk assessment. FTS has largely replaced second trimester screening in many healthcare systems due to its earlier timing and improved detection rates when combined with appropriate counseling and follow-up testing options.
Usage
Usage note: Always written in caps when abbreviated; spell out on first use in documents.
In Context
- "The FTS results indicated a 1:150 risk for trisomy 21, prompting genetic counseling referral." — Prenatal screening report
- "Patient declined FTS but expressed interest in cell-free DNA testing instead." — Clinical documentation