atherogenic index of plasma
A calculated ratio using triglycerides and HDL cholesterol to assess cardiovascular risk from lipid metabolism.
Full Definition
The atherogenic index of plasma (AIP) is calculated as the logarithm of the ratio of triglycerides to HDL cholesterol concentrations (log[TG/HDL-C]). This index provides a measure of the balance between atherogenic and anti-atherogenic lipoproteins and correlates with the predominance of small, dense LDL particles. AIP values are typically classified as low risk (<0.1), intermediate risk (0.1-0.24), and high risk (>0.24). The index has shown strong correlations with cardiovascular outcomes and may be particularly useful in patients with diabetes or metabolic syndrome. AIP provides additional risk stratification beyond traditional lipid parameters and may help identify patients requiring more intensive lipid management.
Usage
Usage note: AIP abbreviation acceptable after first use; specify logarithmic calculation when describing methodology.
In Context
- "The calculated atherogenic index of plasma was 0.31, placing the patient in the high-risk category." — Lipid risk assessment
- "Reduction in the atherogenic index of plasma served as a treatment target alongside traditional lipid goals." — Therapeutic monitoring plan