atherogenic lipoprotein profile
A pattern of lipid abnormalities associated with increased cardiovascular risk, typically involving small dense LDL particles and altered particle composition.
Full Definition
An atherogenic lipoprotein profile refers to a constellation of lipid and lipoprotein abnormalities that promote atherosclerosis and increase cardiovascular risk. This profile typically includes elevated small dense LDL particles, increased apolipoprotein B levels, reduced HDL cholesterol, and often elevated triglycerides. The pattern is commonly seen in metabolic disorders and represents a more nuanced assessment of cardiovascular risk than traditional lipid panels alone.
Usage
Usage note: Use 'lipoprotein profile' rather than 'lipid profile' when referring to particle characteristics.
In Context
- "The patient's atherogenic lipoprotein profile included small dense LDL particles despite normal total cholesterol levels." — Clinical assessment report
- "Advanced lipid testing revealed an atherogenic lipoprotein profile requiring intensive statin therapy." — Laboratory report