coronary flow velocity reserve
Also written as: CFVR — Coronary Flow Velocity Reserve
Ratio of hyperemic to resting coronary flow velocity measured by Doppler echocardiography to assess coronary microvascular function.
Full Definition
Coronary flow velocity reserve (CFVR) is a non-invasive measure of coronary microvascular function obtained through transthoracic Doppler echocardiography of the left anterior descending coronary artery. The measurement involves recording coronary flow velocities at rest and during pharmacologic vasodilation (typically with adenosine or dipyridamole), then calculating the ratio of peak hyperemic to resting flow velocity. Normal CFVR values are typically >2.0, while reduced values may indicate microvascular dysfunction, epicardial coronary stenosis, or both. This measurement is particularly valuable in patients with chest pain and normal or non-obstructive coronary arteries on angiography, helping to identify coronary microvascular disease that may contribute to symptoms and prognosis.
Usage
Usage note: Distinguish from coronary flow reserve, which measures absolute flow rather than velocity ratios.
In Context
- "Coronary flow velocity reserve was reduced at 1.8, suggesting microvascular dysfunction despite normal epicardial arteries." — Echocardiography report
- "Assessment of coronary flow velocity reserve may help identify patients with ischemia and non-obstructive coronary arteries." — Research protocol