MADRS
Also written as: MADRS — Montgomery-Åsberg Depression Rating Scale
A 10-item clinician-rated scale used to assess the severity of depressive symptoms in psychiatric research.
Full Definition
The Montgomery-Åsberg Depression Rating Scale (MADRS) is a widely used clinician-administered assessment tool consisting of 10 items that measure the severity of depressive symptoms. Each item is scored from 0 to 6, providing a total score range of 0-60. Originally developed as an alternative to the Hamilton Depression Rating Scale, MADRS focuses specifically on symptoms that are most responsive to antidepressant treatment. It is frequently used as a primary outcome measure in clinical trials of depression treatments and is valued for its sensitivity to change over time.
Usage
Usage note: Always use the full acronym MADRS, not 'MARS' or other variants. Capitalize all letters.
In Context
- "The primary endpoint was the change from baseline in MADRS total score at week 8." — clinical trial protocol
- "Patients with a MADRS score ≥22 at screening were eligible for randomization." — inclusion criteria