tardive dyskinesia
Pronunciation: TAR-dive dis-ki-NEE-zhah
Involuntary movement disorder that can develop as a side effect of long-term antipsychotic medication use.
Full Definition
Tardive dyskinesia is a serious neurological side effect that can occur after prolonged use of dopamine-blocking medications, particularly typical antipsychotics. It is characterized by repetitive, involuntary movements that most commonly affect the face, lips, tongue, and jaw, but can also involve the limbs and trunk. The movements may include lip smacking, tongue protrusion, facial grimacing, or choreiform movements of the extremities. The condition can be irreversible and may persist even after discontinuation of the offending medication. Risk factors include age, female gender, duration of treatment, and concurrent medical conditions.
Usage
Usage note: Requires careful distinction from other movement disorders and medication side effects.
In Context
- "Regular AIMS assessments are conducted to monitor for signs of tardive dyskinesia." — Medication monitoring protocol
- "The patient developed tardive dyskinesia after fifteen years of haloperidol treatment." — Adverse event report