augmentation therapy
The addition of a second medication to enhance the effectiveness of a primary psychiatric medication that has shown partial response.
Full Definition
Augmentation therapy involves adding a supplementary medication to boost the efficacy of an existing psychiatric treatment that has provided some benefit but incomplete response. This strategy is commonly used in depression treatment when an antidepressant has produced partial improvement but symptoms persist. Common augmentation agents include lithium, thyroid hormones, antipsychotics, and other antidepressants. The goal is to achieve remission while maintaining the benefits already obtained from the primary medication. Documentation should clearly distinguish augmentation from combination therapy and provide rationale for the specific augmenting agent chosen.
Usage
Usage note: Specifically refers to enhancing existing partially effective treatment, not replacing or combining from the start.
In Context
- "Lithium augmentation therapy was initiated to enhance the antidepressant response." — Treatment modification note
- "The patient showed improved outcomes with aripiprazole augmentation therapy for treatment-resistant depression." — Case study