CGIS
Also written as: CGIS — Clinical Global Impression Scale for Schizophrenia
Clinical Global Impression Scale for Schizophrenia, a rating instrument used to assess overall illness severity and treatment response.
Full Definition
The Clinical Global Impression Scale for Schizophrenia (CGIS) is a modified version of the standard CGI scale, specifically adapted for use in schizophrenia clinical trials and practice. It provides a brief, clinician-rated assessment of illness severity, improvement, and efficacy. The scale typically includes severity of illness (CGIS-S) and improvement (CGIS-I) subscales, with ratings from 1 (normal/very much improved) to 7 (extremely ill/very much worse). This instrument is frequently used as a primary or secondary outcome measure in psychopharmacological research.
Usage
Usage note: Distinguish from standard CGI scale; use subscale designations (CGIS-S, CGIS-I) when specific components are referenced.
In Context
- "CGIS-I scores demonstrated significant improvement from baseline to endpoint in the treatment group." — Clinical trial report
- "The primary efficacy endpoint was change in CGIS-S score from baseline to week 8." — Study protocol