cholinesterase inhibitor
Medication that blocks acetylcholine breakdown, used in dementia treatment and to counteract anticholinergic effects.
Full Definition
Medication that blocks the breakdown of acetylcholine by inhibiting cholinesterase enzymes, thereby increasing acetylcholine availability in the brain. In psychopharmacology, these medications are primarily used to treat cognitive symptoms in dementia and sometimes to counteract anticholinergic side effects of other psychiatric medications. Common examples include donepezil, rivastigmine, and galantamine. Editors should note the distinction between acetylcholinesterase inhibitors (primarily central) and butyrylcholinesterase inhibitors.
Usage
Usage note: May be abbreviated as 'ChEI' in some clinical contexts but spell out in formal documents.
In Context
- "The cholinesterase inhibitor improved the patient's cognitive function and reduced confusion." — Geriatric psychiatry note
- "Cholinesterase inhibitor therapy was initiated to address dementia-related symptoms." — Treatment plan