Intermediate
Technical
IVT
rebound effect
Temporary worsening of original symptoms when discontinuing a medication.
Full Definition
Temporary worsening of original symptoms when discontinuing a medication, often occurring within days to weeks of stopping treatment. In psychopharmacology, rebound effects are common with benzodiazepines (rebound anxiety), sleep medications (rebound insomnia), and some antidepressants. Rebound differs from withdrawal syndrome in that it specifically involves return of the originally treated symptoms at levels potentially worse than baseline, while withdrawal can include new symptoms not part of the original condition.
Usage
Usage note: Distinguish from 'withdrawal syndrome' - rebound involves original symptoms, withdrawal may include new ones.
In Context
- "The patient experienced rebound anxiety after abruptly stopping the benzodiazepine." — Clinical progress note
- "Gradual tapering was implemented to minimize rebound effects." — Discontinuation protocol
Also known as
rebound phenomenon
Contrasted with
sustained improvement
Don't confuse with
withdrawal syndrome
relapse
discontinuation syndrome