SNRI
Also written as: SNRI — Serotonin-Norepinephrine Reuptake Inhibitor
Serotonin-norepinephrine reuptake inhibitor, a class of antidepressants that blocks reuptake of both serotonin and norepinephrine.
Full Definition
SNRIs (serotonin-norepinephrine reuptake inhibitors) are a class of antidepressant medications that work by blocking the reuptake of both serotonin and norepinephrine neurotransmitters in the brain. Common examples include venlafaxine, duloxetine, and desvenlafaxine. SNRIs are used to treat major depressive disorder, anxiety disorders, and certain chronic pain conditions. They may be particularly effective for patients who have not responded adequately to SSRIs. Side effects can include nausea, dizziness, increased blood pressure, and discontinuation symptoms if stopped abruptly.
Usage
Usage note: Always written in capital letters as an acronym.
In Context
- "The SNRI was chosen for its dual-action mechanism in treating both depression and neuropathic pain." — medication selection rationale
- "Blood pressure monitoring is recommended when initiating SNRI therapy." — clinical monitoring guidelines