controlled ovarian hyperstimulation
Also written as: COH — Controlled Ovarian Hyperstimulation
Hormone therapy protocol to stimulate multiple egg development for fertility treatments.
Full Definition
Controlled ovarian hyperstimulation (COH) is a fertility treatment protocol that uses injectable hormone medications to stimulate the ovaries to produce multiple mature eggs in a single cycle. This process typically involves gonadotropin-releasing hormone (GnRH) agonists or antagonists to suppress natural hormone production, followed by follicle-stimulating hormone (FSH) and luteinizing hormone (LH) to promote follicle development. The goal is to retrieve multiple eggs for use in IVF or other assisted reproductive procedures, thereby increasing the chances of successful fertilization and pregnancy.
Usage
Usage note: Distinguish from ovarian hyperstimulation syndrome (OHSS), which is a potential complication.
In Context
- "The patient responded well to controlled ovarian hyperstimulation with 12 mature follicles detected on ultrasound." — Medical record
- "Controlled ovarian hyperstimulation protocols must be carefully monitored to prevent complications." — Clinical guideline