Skip to main content
Intermediate Technical IVT

corpus luteum insufficiency

Inadequate progesterone production by the corpus luteum, leading to poor endometrial development and potential pregnancy loss.

Full Definition

Corpus luteum insufficiency, also known as luteal phase insufficiency, occurs when the corpus luteum fails to produce adequate progesterone levels to maintain the endometrium for successful implantation and early pregnancy maintenance. This condition can result in shortened luteal phases, inadequate endometrial development, and increased risk of early pregnancy loss. Diagnosis involves measuring serum progesterone levels during the mid-luteal phase, and treatment typically includes progesterone supplementation. The condition is particularly relevant in assisted reproductive technology cycles where luteal support protocols are routinely implemented.

Usage

Usage note: Distinguish from luteal phase defect, which may have multiple causes.

In Context

  • "Corpus luteum insufficiency was suspected based on the patient's consistently low mid-luteal progesterone levels." — Fertility evaluation report
  • "The treatment protocol included progesterone supplementation to address corpus luteum insufficiency." — Treatment plan documentation

Also known as

luteal phase insufficiency progesterone deficiency

Contrasted with

adequate luteal function

Don't confuse with

luteal phase defect anovulation corpus luteum cyst

Editors from these organisations have used our services since 1998

Reuters BBC Oxford University Press Penguin Random House Springer Microsoft Suncor Energy United Nations Fisher Investments IBM The Home Depot KODAK CHEVRON