poor ovarian response
Inadequate follicular development and low oocyte yield despite appropriate ovarian stimulation protocols.
Full Definition
Poor ovarian response (POR) is defined as an inadequate response to standard ovarian stimulation protocols, typically characterized by the development of fewer than four follicles, retrieval of fewer than four oocytes, or elevated FSH levels indicating diminished ovarian reserve. This condition affects approximately 10-24% of women undergoing IVF and is associated with reduced pregnancy rates and increased cycle cancellation rates. Management often requires modified stimulation protocols and realistic counseling about treatment outcomes.
Usage
Usage note: Formally defined by Bologna criteria. Often abbreviated as 'POR' and synonymous with 'poor responder' in clinical practice.
In Context
- "The patient met criteria for poor ovarian response with only two follicles developing despite maximum stimulation." — Treatment assessment
- "Bologna criteria were used to diagnose poor ovarian response in this challenging case." — Clinical documentation