polar body biopsy
A genetic testing method that analyzes the polar bodies extruded during oocyte maturation to infer the genetic status of the egg.
Full Definition
Polar body biopsy is a preimplantation genetic testing technique that involves the removal and genetic analysis of polar bodies, which are small cells extruded during egg maturation that contain genetic material complementary to the oocyte. This method allows for indirect assessment of the egg's genetic status without directly biopsying the embryo. It is particularly useful for detecting maternal genetic contributions and can help identify eggs suitable for fertilization in patients at risk of transmitting genetic disorders.
Usage
Usage note: Often abbreviated as PB biopsy in clinical documentation.
In Context
- "The clinic offered polar body biopsy as an alternative to embryo biopsy for patients concerned about potential embryo damage." — IVF treatment protocol
- "Polar body biopsy results indicated that 60% of the retrieved oocytes carried the maternal genetic mutation." — Laboratory report