preimplantation genetic testing
Also written as: PGT — Preimplantation Genetic Testing
Genetic analysis of embryos before transfer during IVF to screen for chromosomal abnormalities or specific genetic conditions.
Full Definition
Preimplantation genetic testing (PGT) involves analyzing cells from embryos created through in vitro fertilization before they are transferred to the uterus. This testing can screen for chromosomal abnormalities (PGT-A), single gene disorders (PGT-M), or structural chromosomal rearrangements (PGT-SR). The procedure allows couples to select embryos without specific genetic conditions for transfer, reducing the risk of inherited diseases or pregnancy loss.
Usage
Usage note: Capitalize when used as a proper procedure name; lowercase in general descriptive text.
In Context
- "The couple opted for preimplantation genetic testing to avoid passing on the BRCA1 mutation to their offspring." — Patient consultation notes
- "PGT-A results showed two euploid embryos suitable for transfer." — Laboratory report