triploidy
A chromosomal condition where there are three complete sets of chromosomes (69 total) instead of the normal two sets (46 total).
Full Definition
Triploidy is a chromosomal abnormality characterized by the presence of 69 chromosomes arranged in three complete sets rather than the normal diploid complement of 46 chromosomes in two sets. This condition typically results from fertilization involving either two sperm and one egg, or one sperm and an unreduced egg. Triploidy is usually incompatible with life, often resulting in early miscarriage, though some affected pregnancies may continue longer and be associated with severe maternal complications including preeclampsia.
Usage
Usage note: May be specified by sex chromosome complement (e.g., 69,XXY).
In Context
- "The karyotype revealed triploidy, explaining the severe intrauterine growth restriction observed on ultrasound." — Cytogenetics report
- "Triploidy was suspected based on the ultrasound findings of asymmetric growth restriction and oligohydramnios." — Maternal-fetal medicine consultation