trophectoderm biopsy
Procedure to remove cells from the outer layer of a blastocyst embryo for genetic testing without damaging the inner cell mass.
Full Definition
Trophectoderm biopsy is a specialized technique used in preimplantation genetic testing where several cells are carefully removed from the trophectoderm (the outer cellular layer of a blastocyst embryo that will become the placenta). This procedure is performed on day 5-6 embryos and allows genetic analysis while preserving the inner cell mass that develops into the fetus. The biopsy requires precise micromanipulation techniques and is preferred over earlier embryo biopsy methods because it provides more cells for analysis and has minimal impact on embryo development.
Usage
Usage note: Often abbreviated as 'TE biopsy' in clinical notes; maintain capitalization of 'trophectoderm'.
In Context
- "Trophectoderm biopsy was performed on six blastocysts for PGT-A analysis." — Laboratory procedure notes
- "The embryologist successfully completed trophectoderm biopsy without compromising embryo viability." — IVF cycle documentation