Assisted Hatching
A laboratory technique that creates an opening in the zona pellucida to facilitate embryo implantation.
Full Definition
Assisted hatching is an embryological procedure that involves creating a small opening or thinning in the zona pellucida, the protective shell surrounding the embryo, to help facilitate the natural hatching process and potentially improve implantation rates. The technique can be performed using mechanical, chemical, or laser methods. It is typically recommended for patients with advanced maternal age, previous IVF failures, thick zona pellucida, or frozen embryo transfers where the zona may have hardened during the freezing process.
Usage
Usage note: Distinguish from 'zona pellucida drilling,' which typically refers to the technique used during ICSI.
In Context
- "Assisted hatching was performed using laser technology on day 5 blastocysts." — Laboratory procedure note
- "The clinic's protocol includes assisted hatching for all patients over age 38." — Treatment guideline