controlled ovarian stimulation
The use of fertility medications to stimulate multiple follicle development during an IVF cycle.
Full Definition
Controlled ovarian stimulation (COS) is a fundamental component of IVF treatment that involves using fertility medications to override the body's natural selection of a single dominant follicle. Instead, multiple follicles are stimulated to develop simultaneously, allowing for the retrieval of multiple eggs in one cycle. This process typically involves gonadotropins (FSH/LH) and may include GnRH agonists or antagonists to prevent premature ovulation. The goal is to maximize the number of mature eggs while minimizing risks such as ovarian hyperstimulation syndrome.
Usage
Usage note: Often abbreviated as COS in clinical contexts.
In Context
- "The controlled ovarian stimulation protocol was adjusted based on the patient's AMH levels." — Treatment plan
- "Monitoring during controlled ovarian stimulation includes serial ultrasounds and hormone levels." — Clinical guideline