vitrification
Pronunciation: vit-ri-fi-KAY-shun
An ultra-rapid freezing technique used to cryopreserve eggs, sperm, and embryos by converting water directly to a glass-like state.
Full Definition
Vitrification is an advanced cryopreservation method that achieves extremely rapid cooling rates to prevent ice crystal formation during freezing. Unlike traditional slow-freeze methods, vitrification uses high concentrations of cryoprotectants and ultra-rapid cooling to create a glass-like solid state. This technique has revolutionized fertility preservation, offering superior survival rates for eggs and embryos compared to conventional freezing methods. The process requires careful timing and expertise, as cells must be rapidly plunged into liquid nitrogen while avoiding toxic effects from cryoprotectants.
Usage
Usage note: Not capitalized unless beginning a sentence; distinct from other freezing methods.
In Context
- "The clinic uses vitrification for all embryo freezing procedures due to superior survival rates." — Laboratory protocol
- "Egg vitrification has made fertility preservation more accessible for cancer patients." — Medical journal