cytoreductive surgery
Surgical procedure aimed at removing maximum tumor burden, often followed by heated chemotherapy.
Full Definition
Cytoreductive surgery is a complex surgical procedure designed to remove all visible tumor tissue, typically followed by hyperthermic intraperitoneal chemotherapy (HIPEC) for peritoneal carcinomatosis. In surgical critical care, these patients require intensive monitoring due to the extensive nature of the surgery, significant fluid shifts, potential for coagulopathy, and risk of multi-organ dysfunction. The procedure involves peritonectomy and organ resection to achieve complete cytoreduction, followed by heated chemotherapy circulation within the peritoneal cavity. Post-operative care focuses on managing third-spacing, renal function, and systemic chemotherapy effects.
Usage
Usage note: Often abbreviated as CRS in combination with HIPEC procedures.
In Context
- "The patient underwent cytoreductive surgery with HIPEC for peritoneal carcinomatosis." — Operative report
- "Post-operative management after cytoreductive surgery requires careful fluid balance monitoring." — ICU protocol