papillary renal cell carcinoma
Also written as: pRCC — papillary renal cell carcinoma
Second most common subtype of kidney cancer characterized by papillary growth pattern and generally better prognosis.
Full Definition
Papillary renal cell carcinoma (pRCC) accounts for approximately 10-15% of all renal cell carcinomas and is characterized by a distinctive papillary architecture on microscopic examination. This subtype is further classified into Type 1 and Type 2, with Type 1 typically having a more favorable prognosis. pRCC tends to be multifocal and bilateral more often than clear cell RCC and is associated with specific genetic alterations. The tumor often appears as a well-circumscribed, encapsulated mass with a tan to yellow cut surface. Treatment follows standard principles of renal cell carcinoma management, but the generally better prognosis may influence surveillance strategies.
Usage
Usage note: Hyphenate all components when used as a compound adjective. May be abbreviated as pRCC in specialized literature.
In Context
- "Histopathology confirmed papillary renal cell carcinoma, Type 1, with negative margins." — Pathology report
- "The patient's family history of papillary renal cell carcinoma prompted genetic counseling." — Clinical note