penile cancer
Malignant tumor affecting the penis, most commonly squamous cell carcinoma.
Full Definition
A rare urologic malignancy primarily affecting the glans, foreskin, or shaft of the penis, with squamous cell carcinoma comprising over 95% of cases. Risk factors include poor hygiene, phimosis, HPV infection, and smoking. The disease typically spreads through lymphatic channels to inguinal and pelvic lymph nodes. Early-stage disease may be treated with organ-sparing procedures, while advanced cases may require partial or total penectomy.
Usage
Usage note: Use 'penile cancer' rather than 'cancer of the penis' in technical contexts.
In Context
- "The patient presented with a suspicious penile lesion concerning for penile cancer." — Clinical assessment
- "HPV vaccination may reduce the incidence of penile cancer in endemic regions." — Prevention guideline