positive surgical margin
Presence of cancer cells at the inked edge of a surgical specimen, indicating incomplete tumor removal.
Full Definition
A positive surgical margin occurs when cancer cells are present at the inked surface of a surgically resected specimen, indicating that tumor extends to the edge of the resection. In urologic oncology, positive margins are most commonly discussed in the context of radical prostatectomy, partial nephrectomy, and radical cystectomy. The presence of positive margins is associated with increased risk of local recurrence and may necessitate additional treatment such as adjuvant radiation therapy. Margin status is a critical component of pathologic staging and influences both prognosis and subsequent treatment decisions.
Usage
Usage note: Distinguish from close margins, which are negative but within a specified distance from the tumor. May be reported with specific location and extent.
In Context
- "A positive surgical margin was identified at the left posterolateral aspect of the prostate specimen." — Pathology report
- "The presence of a positive surgical margin prompted referral to radiation oncology for adjuvant therapy consideration." — Post-operative note