salvage radiation therapy
Also written as: SRT — salvage radiation therapy
Radiation treatment delivered to the prostate bed following radical prostatectomy for biochemical or local recurrence.
Full Definition
Salvage radiation therapy (SRT) involves the delivery of external beam radiation to the prostate bed and potentially regional lymph nodes following radical prostatectomy in patients who develop biochemical or local recurrence. This treatment modality aims to eradicate residual microscopic disease and achieve durable cancer control in the post-operative setting. The optimal timing of SRT is controversial, with evidence supporting early intervention at lower PSA levels for maximum efficacy. Treatment planning requires careful consideration of prior surgical anatomy, risk of local versus distant recurrence, and potential toxicity to surrounding structures including the bladder and rectum.
Usage
Usage note: Distinguish from adjuvant radiation therapy, which is given immediately post-surgery regardless of PSA status.
In Context
- "Salvage radiation therapy was initiated at a PSA of 0.4 ng/mL to optimize cancer control outcomes." — Radiation oncology consultation
- "The patient completed salvage radiation therapy with 66 Gy delivered to the prostate bed over 7 weeks." — Treatment completion summary