Peyronie disease
Pronunciation: pay-roh-NEEZ
Connective tissue disorder causing fibrous plaques in the penile tunica albuginea, resulting in penile curvature and potential erectile dysfunction.
Full Definition
A connective tissue disorder characterized by the formation of fibrous plaques within the tunica albuginea of the corpora cavernosa, leading to penile deformity, curvature, and often erectile dysfunction. The condition typically progresses through acute and chronic phases, with the acute phase involving pain and progressive deformity, followed by plaque stabilization. Etiology remains unclear but may involve trauma, genetic factors, and autoimmune processes. Treatment options include medical therapy with collagenase injections, mechanical therapy, and surgical correction for severe cases.
Usage
Usage note: Named condition; capitalize appropriately. Specify degree of curvature and phase when documenting.
In Context
- "The patient with Peyronie disease demonstrated 45-degree dorsal curvature with palpable plaque." — Urologic examination
- "Collagenase clostridium histolyticum injection was administered for Peyronie disease treatment." — Treatment note