scaffold thrombosis
Blood clot formation within a bioresorbable coronary scaffold, representing a device-specific complication.
Full Definition
Scaffold thrombosis refers to the formation of blood clots within or around a bioresorbable vascular scaffold (BVS), representing a serious complication specific to these newer generation devices. Unlike traditional metallic stent thrombosis, scaffold thrombosis may be influenced by the unique properties of the polymer struts, including their thickness, degradation process, and altered flow dynamics. The incidence appears higher than with drug-eluting stents, particularly in the early post-implantation period. Risk factors include undersizing, malapposition, and discontinuation of dual antiplatelet therapy. Recognition and treatment require understanding of the scaffold's mechanical properties and degradation timeline.
Usage
Usage note: Hyphenate as compound noun; distinguish from traditional metallic stent thrombosis in mechanism and risk factors.
In Context
- "The patient presented with acute MI secondary to scaffold thrombosis at 3 months post-implantation." — Case report
- "OCT imaging confirmed scaffold thrombosis with evidence of strut malapposition." — Diagnostic report