post-thrombotic syndrome
Also written as: PTS — post-thrombotic syndrome
Chronic venous insufficiency and associated symptoms developing after deep vein thrombosis due to valvular incompetence and venous obstruction.
Full Definition
Post-thrombotic syndrome (PTS) is a chronic complication of deep vein thrombosis characterized by persistent symptoms and signs of chronic venous insufficiency. The condition results from a combination of venous obstruction due to incomplete thrombus resolution and valvular incompetence from inflammatory damage during the acute thrombotic event. Symptoms include leg swelling, pain, heaviness, and in severe cases, venous ulceration. PTS affects 20-50% of patients following DVT and significantly impacts quality of life. Prevention strategies include appropriate anticoagulation, compression therapy, and early mobilization, while treatment focuses on symptom management and preventing progression to venous ulceration.
Usage
Usage note: Always hyphenate; may be abbreviated as PTS in subsequent references after full term is established.
In Context
- "The patient developed post-thrombotic syndrome six months after her initial deep vein thrombosis." — follow-up visit note
- "Compression stockings are recommended to prevent post-thrombotic syndrome in DVT patients." — discharge instructions