adenosine

Full Definition

Adenosine is a naturally occurring nucleoside that acts as an ultra-short-acting antiarrhythmic agent. It works by causing transient AV block through activation of adenosine receptors in cardiac tissue. The drug has a half-life of less than 10 seconds and is primarily used in emergency settings to convert supraventricular tachycardias to normal sinus rhythm. Its rapid onset and offset make it particularly valuable for diagnostic purposes in distinguishing between different types of tachyarrhythmias.

Usage

Usage note: Always specify route and rate of administration; distinguish from adenine.

In Context

• "The emergency physician administered 6 mg of adenosine via rapid IV push to terminate the patient's supraventricular tachycardia." — Emergency department report
• "Adenosine was ineffective in converting the wide-complex tachycardia, suggesting ventricular origin." — Cardiology consultation note