reactive lymphadenopathy
Pronunciation: re-AK-tiv lim-fad-uh-NOP-uh-thee
Enlargement of lymph nodes due to benign inflammatory response rather than malignant involvement.
Full Definition
Reactive lymphadenopathy refers to the enlargement of lymph nodes caused by benign inflammatory or immune responses rather than malignant infiltration. In breast cancer patients, reactive lymphadenopathy can occur in axillary, supraclavicular, or internal mammary lymph nodes due to infection, inflammation, or immune system activation. This condition can complicate staging and treatment planning, as enlarged lymph nodes may mimic metastatic disease on imaging. Tissue sampling through fine needle aspiration or core biopsy may be necessary to distinguish reactive changes from malignant involvement, particularly when lymph node enlargement is the only concerning finding.
Usage
Usage note: Specify location and any clinical context that may explain the reactive changes.
In Context
- "Axillary ultrasound showed enlarged lymph nodes consistent with reactive lymphadenopathy rather than metastatic disease." — Radiology report
- "Fine needle aspiration confirmed reactive lymphadenopathy with no evidence of malignant cells." — Cytology report