enzymatic necrosectomy
Non-surgical removal of burn eschar using proteolytic enzymes applied topically.
Full Definition
Enzymatic necrosectomy is a non-surgical method for removing necrotic tissue from burn wounds using topically applied proteolytic enzymes such as collagenase or bromelain-based preparations. This technique selectively digests necrotic collagen while preserving viable tissue, making it particularly useful for burns in anatomically sensitive areas or in patients who are poor surgical candidates. The process is slower than surgical debridement but may result in better preservation of viable tissue and reduced need for extensive grafting. It requires careful monitoring for signs of infection and may be combined with other debridement methods.
Usage
Usage note: More specific than general 'enzymatic debridement'; refers specifically to eschar removal.
In Context
- "Enzymatic necrosectomy was chosen for the facial burns to minimize tissue loss and scarring." — Plastic surgery consultation
- "The collagenase ointment used for enzymatic necrosectomy showed effective eschar dissolution over 72 hours." — Wound care progress note