Adenosine Challenge
A diagnostic test using intravenous adenosine to unmask concealed accessory pathways or confirm AV nodal-dependent arrhythmias.
Full Definition
Adenosine challenge involves the administration of intravenous adenosine during electrophysiology study to temporarily block AV nodal conduction. This pharmacologic intervention helps distinguish between different tachycardia mechanisms by revealing concealed accessory pathways that may not be apparent during baseline rhythm. The test is particularly valuable in differentiating supraventricular tachycardias and assessing the contribution of the AV node to the arrhythmia circuit. Adenosine's ultra-short half-life makes it ideal for this diagnostic application.
Usage
Usage note: Capitalize 'Adenosine' when referring to the drug name, lowercase when describing the endogenous compound.
In Context
- "The adenosine challenge revealed a concealed left lateral accessory pathway that was not evident during sinus rhythm." — EP study report
- "Following adenosine challenge, the tachycardia terminated with AV block, confirming AV nodal dependence." — Clinical documentation