arterial stiffness
Reduced elasticity of arterial walls, measured as a marker of cardiovascular risk in cardiometabolic disease.
Full Definition
Arterial stiffness refers to the loss of arterial elasticity and compliance, commonly measured using pulse wave velocity or augmentation index. In cardiometabolic medicine, arterial stiffness serves as an important surrogate marker for cardiovascular disease risk and is frequently elevated in patients with diabetes, hypertension, and metabolic syndrome. Increased arterial stiffness is associated with enhanced cardiac workload and reduced coronary perfusion, making it both a consequence and contributor to cardiovascular disease progression.
Usage
Usage note: Often quantified using specific metrics like pulse wave velocity (PWV) or augmentation index (AIx).
In Context
- "Arterial stiffness measurements showed significant improvement following six months of intensive glucose control." — Clinical research report
- "The patient's elevated arterial stiffness index warranted aggressive cardiovascular risk factor modification." — Clinical assessment note