inotropic support
Pronunciation: in-oh-TROP-ik suh-PORT
Pharmacological support using medications that increase myocardial contractility to improve cardiac output in patients with heart failure.
Full Definition
Inotropic support refers to the use of medications that enhance myocardial contractility to improve cardiac output and hemodynamic stability, particularly in patients with heart failure or low cardiac output states. Common inotropic agents include dobutamine, dopamine, epinephrine, and milrinone, each with different mechanisms of action and hemodynamic profiles. This support is frequently required during cardiac surgery, especially after cardiopulmonary bypass when myocardial dysfunction may occur. The choice of inotropic agent depends on the specific hemodynamic goals and patient condition. Medical editors should distinguish between positive inotropic effects (increased contractility) and chronotropic effects (increased heart rate).
Usage
Usage note: Distinguish from vasopressor support, which primarily affects vascular tone rather than contractility.
In Context
- "The patient required high-dose inotropic support to maintain adequate cardiac output following valve replacement surgery." — clinical note
- "Weaning from inotropic support was achieved gradually over the first postoperative day." — progress note