Bundle of His
Pronunciation: BUN-dul of HISS
Specialized cardiac conduction tissue that transmits electrical impulses from the atrioventricular node to the ventricles.
Full Definition
The Bundle of His is a crucial component of the cardiac conduction system, consisting of specialized myocardial fibers that conduct electrical impulses from the AV node to the bundle branches. Located in the membranous portion of the interventricular septum, this structure is essential for coordinated ventricular contraction. Pathological changes to the Bundle of His, including fibrosis, infiltration, or congenital abnormalities, can result in various degrees of heart block. Histologically, it appears as a discrete collection of specialized conducting fibers surrounded by fibrous tissue.
Usage
Usage note: Always capitalize 'His' as it is an eponym. Use 'Bundle of His' rather than 'His bundle' in formal reports.
In Context
- "Extensive fibrosis of the Bundle of His was identified as the cause of complete heart block." — Autopsy report
- "The Bundle of His showed normal morphology with intact specialized conducting fibers." — Cardiac pathology assessment