ARB
Also written as: ARB — angiotensin receptor blocker
Angiotensin receptor blocker, a class of antihypertensive medications that block angiotensin II receptors.
Full Definition
Angiotensin receptor blockers (ARBs) are a class of medications that lower blood pressure by blocking the action of angiotensin II at the AT1 receptor. Unlike ACE inhibitors, ARBs do not affect bradykinin metabolism and therefore have a lower incidence of cough as a side effect. Common ARBs include losartan, valsartan, and telmisartan. In cardiovascular prevention, ARBs are used to treat hypertension and provide cardiovascular protection, particularly in patients with diabetes or chronic kidney disease. They are often prescribed as an alternative to ACE inhibitors in patients who experience cough.
Usage
Usage note: Use all caps for the acronym. Distinguish clearly from ACE inhibitors in clinical context.
In Context
- "The patient was switched from an ACE inhibitor to an ARB due to persistent cough." — Medication adjustment note
- "ARB therapy was initiated for both blood pressure control and renal protection." — Treatment plan