acute vessel closure
Complete occlusion of a coronary artery during or immediately after percutaneous coronary intervention.
Full Definition
Acute vessel closure is defined as complete occlusion of a coronary artery occurring during or within 24 hours of percutaneous coronary intervention, typically manifested as TIMI flow grade 0 or 1. This serious procedural complication can result from various mechanisms including coronary dissection, acute thrombosis, elastic recoil, or vasospasm. Acute vessel closure often presents clinically with chest pain, ST-segment changes, and hemodynamic compromise, requiring immediate intervention to restore coronary flow. The incidence of acute vessel closure has decreased significantly with the introduction of coronary stents and improved antiplatelet therapy regimens. When acute vessel closure occurs, treatment options include repeat balloon inflation, stent implantation, thrombus aspiration, or emergency coronary artery bypass surgery in refractory cases. This complication is associated with increased risk of periprocedural myocardial infarction and adverse clinical outcomes.
Usage
Usage note: Specify the timing and mechanism of closure when reporting acute vessel closure events.
In Context
- "Acute vessel closure occurred in 0.8% of procedures, requiring immediate re-intervention." — Procedural complications study
- "The patient developed acute vessel closure requiring emergent stent implantation." — Case report