angiographic restenosis
Narrowing of a previously treated coronary artery segment as visualized on coronary angiography, typically defined as ≥50% diameter stenosis.
Full Definition
Angiographic restenosis refers to the re-narrowing of a coronary artery segment that has undergone previous intervention, as demonstrated by coronary angiography. This endpoint is commonly defined as ≥50% diameter stenosis at the treated segment during follow-up angiography. In cardiovascular device trials, angiographic restenosis serves as a key efficacy endpoint, particularly in studies comparing different stent technologies. The measurement requires quantitative coronary angiography (QCA) for precise assessment and is distinct from clinical restenosis, which involves symptom recurrence.
Usage
Usage note: Distinguish from clinical restenosis; always specify the threshold percentage (typically 50%) and measurement method.
In Context
- "The primary endpoint was angiographic restenosis at 6-month follow-up angiography." — clinical trial protocol
- "Drug-eluting stents significantly reduced angiographic restenosis rates compared to bare-metal stents." — research publication