antiplatelet therapy
Medication regimen using drugs that inhibit platelet aggregation to prevent thrombotic cardiovascular events.
Full Definition
Antiplatelet therapy involves the use of medications that interfere with platelet function and aggregation, thereby reducing the risk of arterial thrombosis and subsequent cardiovascular events. Common antiplatelet agents include aspirin, clopidogrel, ticagrelor, and prasugrel, often used in combination as dual antiplatelet therapy (DAPT). In cardiovascular research, antiplatelet therapy regimens are frequently studied as interventions, with variations in drug selection, dosing, and duration serving as primary study variables. The optimal duration and intensity of antiplatelet therapy remain active areas of investigation, particularly following percutaneous coronary intervention or acute coronary syndromes.
Usage
Usage note: Specify individual agents and dosing when describing study protocols.
In Context
- "All patients received standard dual antiplatelet therapy with aspirin and clopidogrel for 12 months." — Treatment protocol
- "The primary endpoint was major bleeding events related to antiplatelet therapy." — Safety endpoint definition