Professional Formal IVT

clinical event committee

Also written as: CEC — clinical event committee

Independent group of medical experts who adjudicate and classify cardiovascular events in clinical trials.

Full Definition

A clinical event committee (CEC) is an independent panel of clinical experts responsible for the systematic review, classification, and adjudication of cardiovascular events reported in clinical trials. Committee members are typically blinded to treatment assignment and use pre-specified criteria and supporting documentation to determine whether reported events meet protocol-defined endpoint criteria. The CEC process ensures standardized, unbiased evaluation of clinical outcomes and enhances the scientific rigor of trial results. Common adjudicated events include myocardial infarction, stroke, cardiovascular death, and heart failure hospitalizations.

Usage

Usage note: Specify committee composition and blinding procedures when describing adjudication methods.

In Context

"All suspected cardiovascular events were adjudicated by an independent clinical event committee." — Adjudication methodology
"The clinical event committee consisted of three cardiologists blinded to treatment assignment." — Committee composition

Also known as

CEC endpoint adjudication committee clinical events adjudication committee

Don't confuse with

data safety monitoring board steering committee

CEC ← Back to glossary clinical events classification