target vessel revascularization
Any repeat percutaneous or surgical intervention involving the specific coronary vessel that was treated in the index procedure.
Full Definition
Target vessel revascularization (TVR) is a key safety and efficacy endpoint in cardiovascular research, particularly in studies evaluating percutaneous coronary interventions and drug-eluting stents. TVR includes any repeat revascularization procedure (percutaneous or surgical) performed on the target vessel due to restenosis, progression of disease, or acute complications. This endpoint differs from target lesion revascularization (TLR), which specifically refers to repeat procedures within the treated segment plus 5mm proximally and distally. TVR rates are commonly reported at 30 days, 1 year, and longer follow-up periods to assess long-term device or treatment efficacy.
Usage
Usage note: Distinguish clearly from 'target lesion revascularization' which has a more specific anatomical definition.
In Context
- "The primary safety endpoint was target vessel revascularization at 12 months." — Clinical trial design
- "Target vessel revascularization rates were significantly lower in the drug-eluting stent group compared to bare metal stents." — Research results