target vessel failure
Also written as: TVF — Target Vessel Failure
Composite endpoint including cardiac death, target vessel-related myocardial infarction, or target vessel revascularization.
Full Definition
Target vessel failure (TVF) is a commonly used composite endpoint in cardiovascular research that encompasses any adverse cardiac event related to the treated vessel. It includes cardiac death related to the target vessel, myocardial infarction attributed to the target vessel, and any repeat revascularization of the target vessel. TVF provides a comprehensive assessment of vessel-specific outcomes and is particularly important in interventional cardiology studies evaluating stent performance or procedural techniques. This endpoint helps distinguish between device-related complications and those occurring in non-treated vessels.
Usage
Usage note: Always specify the time frame when reporting TVF rates.
In Context
- "The primary endpoint was target vessel failure at 12 months." — Clinical trial protocol
- "Target vessel failure occurred in 8.3% of patients in the intervention group." — Results manuscript