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gliosis
Pronunciation: gly-OH-sis
Proliferation of glial cells in response to central nervous system injury or disease.
Full Definition
Gliosis represents the brain's response to injury, characterized by the multiplication and hypertrophy of astrocytes and other glial cells. This process forms glial scars that can be seen on imaging studies and pathological examination. Gliosis occurs in various neurological conditions including trauma, infection, ischemia, and neurodegenerative diseases, serving both protective and potentially harmful functions.
Usage
Usage note: Not a tumor; refers to reactive cellular changes. Distinguish from gliomas which are neoplastic.
In Context
- "MRI showed extensive gliosis in the periventricular white matter." — Radiology report
- "Chronic gliosis may impede neural regeneration following injury." — Pathology assessment
Also known as
glial scarring
reactive gliosis
Contrasted with
normal glial architecture
Don't confuse with
glioma
glioblastoma