bilateral adrenalectomy
Surgical removal of both adrenal glands, typically performed for hereditary pheochromocytoma syndromes or bilateral disease.
Full Definition
Bilateral adrenalectomy involves surgical removal of both adrenal glands and represents a major therapeutic intervention requiring lifelong hormone replacement therapy. This procedure is most commonly indicated in patients with hereditary pheochromocytoma-paraganglioma syndromes who develop bilateral pheochromocytomas, or in cases of bilateral metastatic disease. Post-operative management requires immediate glucocorticoid and mineralocorticoid replacement, with careful monitoring for adrenal crisis. The decision for bilateral adrenalectomy requires extensive counseling about lifelong medical dependency and emergency management.
Usage
Usage note: Always mention need for lifelong hormone replacement when discussing this procedure.
In Context
- "The patient with MEN2A syndrome underwent bilateral adrenalectomy for synchronous pheochromocytomas." — Operative report
- "Post-bilateral adrenalectomy, the patient required emergency management protocols for potential adrenal insufficiency." — Discharge planning