carcinoid crisis
Life-threatening complication characterized by severe vasomotor symptoms in patients with carcinoid syndrome.
Full Definition
Carcinoid crisis is a potentially fatal acute exacerbation of carcinoid syndrome symptoms, typically triggered by anesthesia, surgery, stress, or certain medications in patients with functional neuroendocrine tumors. The crisis presents with severe flushing, hypotension, bronchospasm, altered mental status, and cardiac dysfunction due to massive release of vasoactive substances. Prevention involves preoperative administration of octreotide and careful avoidance of precipitating drugs. Recognition and immediate treatment with octreotide, supportive care, and management of cardiovascular collapse are crucial for patient survival. The condition underscores the importance of perioperative planning in patients with known functional NETs.
Usage
Usage note: Requires immediate recognition and octreotide administration; potentially fatal if untreated.
In Context
- "Perioperative octreotide was administered to prevent carcinoid crisis during tumor resection." — anesthesia record
- "The patient developed carcinoid crisis following contrast administration." — emergency department note