catecholamine crisis
Life-threatening hypertensive emergency caused by massive catecholamine release from pheochromocytoma or paraganglioma.
Full Definition
Catecholamine crisis represents a medical emergency characterized by severe hypertension, tachycardia, and potential cardiovascular collapse due to excessive catecholamine release from pheochromocytoma or paraganglioma. This crisis may be precipitated by physical manipulation of the tumor, certain medications, anesthesia, or spontaneous tumor hemorrhage. Clinical manifestations include severe headache, profuse sweating, chest pain, and potential stroke or cardiac arrhythmias. Management requires immediate alpha-blockade followed by beta-blockade, with careful monitoring in intensive care settings. Recognition and prompt treatment are crucial to prevent fatal outcomes.
Usage
Usage note: Distinguish from other endocrine emergencies like carcinoid crisis.
In Context
- "Intraoperative manipulation triggered a catecholamine crisis requiring immediate alpha-blockade." — Anesthesia record
- "The patient's catecholamine crisis resolved following tumor removal and supportive care." — Post-operative note