Intermediate
Technical
IVT
catecholamine excess
Pathological overproduction of epinephrine and norepinephrine, typically by pheochromocytomas or paragangliomas.
Full Definition
Catecholamine excess refers to the abnormally high levels of epinephrine, norepinephrine, and their metabolites produced by chromaffin cell tumors. This biochemical hallmark of pheochromocytomas and paragangliomas causes the characteristic symptoms of hypertension, palpitations, sweating, and headaches. Diagnosis is confirmed through measurement of plasma or urinary catecholamines and their metabolites, particularly metanephrines.
Usage
Usage note: Distinguish from other hormone excess syndromes by specifying the catecholamine pathway.
In Context
- "Laboratory findings confirmed catecholamine excess with elevated plasma metanephrines exceeding ten times the upper reference limit." — Pathology report
- "Preoperative alpha-blockade is essential in patients with catecholamine excess to prevent hypertensive crisis during surgery." — Surgical planning document
Also known as
catecholamine overproduction
chromaffin cell hyperfunction
Contrasted with
catecholamine deficiency
Don't confuse with
carcinoid syndrome
thyrotoxicosis