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In the Industry Vocabulary Test
chromogranin A
Pronunciation: KROH-moh-gran-in
A protein biomarker used to diagnose and monitor neuroendocrine tumors.
Full Definition
Chromogranin A (CgA) is a glycoprotein found in secretory vesicles of neuroendocrine cells and serves as a widely used biomarker for neuroendocrine tumors. Elevated serum levels can indicate the presence of NETs and are used for both initial diagnosis and monitoring treatment response. However, CgA levels can also be elevated in other conditions and with certain medications, requiring careful interpretation in clinical context.
Usage
Usage note: Always capitalize the 'A' when abbreviated as CgA.
In Context
- "Serum chromogranin A levels were significantly elevated at 450 ng/mL." — laboratory report
- "The tumor showed strong positive staining for chromogranin A on immunohistochemistry." — pathology report
Also known as
CgA
chromogranin-A
Don't confuse with
chromogranin B
synaptophysin