Ileal NET
A neuroendocrine tumor arising from the terminal small bowel, the most common location for small intestinal NETs.
Full Definition
Ileal neuroendocrine tumors are the most common type of small bowel NETs, arising from enterochromaffin cells in the terminal ileum. These tumors frequently present with metastatic disease due to their tendency for early spread to regional lymph nodes and liver. Many ileal NETs secrete serotonin and other vasoactive substances, potentially causing carcinoid syndrome when hepatic metastases are present. The primary tumor is often small and may be difficult to detect on imaging, while metastases can be extensive. Treatment typically involves surgical resection when feasible, along with somatostatin analogs for symptom control and potential antitumor effects.
Usage
Usage note: Specify anatomical location clearly; distinguish from other small bowel NET locations.
In Context
- "CT enterography revealed a small ileal NET with multiple hepatic metastases and mesenteric lymphadenopathy." — Radiology report
- "The patient underwent right hemicolectomy for resection of the ileal NET and involved mesentery." — Operative report